Complement consumption gonococcal peptidoglycan
نویسندگان
چکیده
منابع مشابه
Evaluation of the gonococcal complement-fixation test.
The gonococcal complement-fixation test (GCFT), based on the same principle as the Wassermann reaction (WR), has been in use for over 60 years. The test was applied for the first time, using a culture of the gonococcus as antigen, by Muller and Oppenheim (1906) to establish the diagnosis in a case of arthritis. Teague and Torrey (1907) suggested that negative results in the GCFT were due to dif...
متن کاملGonococcal lipooligosaccharide sialylation prevents complement-dependent killing by immune sera.
Previous investigators have demonstrated that a sialic acid residue is added to the terminal galactose moiety of gonococcal lipooligosaccharide (LOS) when incubated with 5'-CMP-N-acetylneuraminic acid. When this in vitro sialylation occurs, gonococci become resistant to the bactericidal activity of normal human serum. This is believed to result because the added sialic acid residue blocks the b...
متن کاملGonococcal Complement-fixation Test in Complicated and Uncomplicated Gonorrhoea.
The complement-fixation reaction with gonococcal antigen (gonococcal complement-fixation test: GCFI) is based on the same serological principle, and has been known for about as long, as the Wassermann reaction. Up to the 1940's the GCFT was widely employed, but as improvements in cultivation techniques for gonococci were developed, interest in the complement-fixation reaction diminished. At pre...
متن کاملStrain-related differences in lysozyme sensitivity and extent of O-acetylation of gonococcal peptidoglycan.
Peptidoglycan from Neisseria gonorrhoeae RD5 was completely degraded by hen egg white lysozyme and was not extensively O-acetylated. In contrast, peptidoglycans from gonococcal strains FA19 and FA102 (a penicillin-resistant mutant derived from FA19), were markedly resistant to digestion by hen egg white lysozyme and were extensively O-acetylated.
متن کاملGonococcal arthritis (disseminated gonococcal infection).
Septic arthritis caused by N gonorrhoeae is monoarticular or pauciarticular, and is more commonly associated with positive synovial fluid cultures and negative blood cultures. Gonococcal bacteremia is more likely to be associated with polyarthralgias and skin lesions. The diagnosis of gonococcal arthritis or DGI is also secure if a mucosal gonococcal infection is documented in the presence of a...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1982
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.35.2.442-448.1982